Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C30H18O10 |
| Molecular Weight | 538.4579 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OC1=CC=C(C=C1)C2=CC(=O)C3=C(O)C=C(O)C(C4=CC(=CC=C4O)C5=CC(=O)C6=C(O)C=C(O)C=C6O5)=C3O2
InChI
InChIKey=YUSWMAULDXZHPY-UHFFFAOYSA-N
InChI=1S/C30H18O10/c31-15-4-1-13(2-5-15)24-12-23(38)29-21(36)10-20(35)27(30(29)40-24)17-7-14(3-6-18(17)33)25-11-22(37)28-19(34)8-16(32)9-26(28)39-25/h1-12,31-36H
| Molecular Formula | C30H18O10 |
| Molecular Weight | 538.4579 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Structurally unique biflavonoids from Selaginella chrysocaulos and Selaginella bryopteris. | 2006 Apr |
|
| Mutagenic activity promoted by amentoflavone and methanolic extract of Byrsonima crassa Niedenzu. | 2006 Aug 1 |
|
| In vitro peroxynitrite scavenging activity of 6-hydroxykynurenic acid and other flavonoids from Gingko biloba yellow leaves. | 2006 Dec |
|
| Effects of St. John's wort extract and single constituents on stress-induced hyperthermia in mice. | 2006 Dec |
|
| Natural health products that inhibit angiogenesis: a potential source for investigational new agents to treat cancer-Part 1. | 2006 Feb |
|
| [Determination of amentoflavone in 11 species of Selaginella medicinal material by HPLC]. | 2006 Jan |
|
| Iridoid glucosides from Viburnum chinshanense. | 2006 Jul 10 |
|
| Natural health products that inhibit angiogenesis: a potential source for investigational new agents to treat cancer-Part 2. | 2006 Jun |
|
| Antifungal effect of amentoflavone derived from Selaginella tamariscina. | 2006 Sep |
|
| Amentoflavone, a biflavonoid from Biophytum sensitivum augments lymphocyte proliferation, natural killer cell and antibody dependent cellular cytotoxicity through enhanced production of IL-2 and IFN-gamma and restrains serum sialic acid and gamma glutamyl transpeptidase production in tumor - bearing animals. | 2007 |
|
| [Studies on flavonoids from stems and leaves of Calophyllum inophyllum]. | 2007 Apr |
|
| Phytochemical investigation and hepatoprotective activity of Cupressus sempervirens L. leaves growing in Egypt. | 2007 Aug |
|
| Flavonoids and biflavonoids in Tuscan berries of Juniperus communis L.: detection and quantitation by HPLC/DAD/ESI/MS. | 2007 Aug 8 |
|
| Evaluation of proinflammatory cytokine pathway inhibitors for p38 MAPK inhibitory potential. | 2007 Dec 13 |
|
| Protein tyrosine phosphatase 1B inhibitory activity of amentoflavone and its cellular effect on tyrosine phosphorylation of insulin receptors. | 2007 Feb |
|
| Antimalarial and vasorelaxant constituents of the leaves of Allanblackia monticola (Guttiferae). | 2007 Jan |
|
| In silico prediction of pregnane X receptor activators by machine learning approaches. | 2007 Jan |
|
| Effect of amentoflavone on the inhibition of pulmonary metastasis induced by B16F-10 melanoma cells in C57BL/6 mice. | 2007 Jun |
|
| Antiulcerogenic effect and acute toxicity of a hydroethanolic extract from the cashew (Anacardium occidentale L.) leaves. | 2007 Jun 13 |
|
| Mutagenic evaluation and chemical investigation of Byrsonima intermedia A. Juss. leaf extracts. | 2007 Jun 13 |
|
| Constituents and antiulcer effect of Alchornea glandulosa: activation of cell proliferation in gastric mucosa during the healing process. | 2007 Mar |
|
| Topical anti-inflammatory activity of extracts and compounds from Hypericum perforatum L. | 2007 May |
|
| New constituent from Podocarpus macrophyllus var. macrophyllus shows anti-tyrosinase effect and regulates tyrosinase-related proteins and mRNA in human epidermal melanocytes. | 2007 May |
|
| [Study on HPLC fingerprint characteristics of Selaginella plants]. | 2007 Oct |
|
| S-phase accumulation of Candida albicans by anticandidal effect of amentoflavone isolated from Selaginella tamariscina. | 2007 Oct |
|
| Biflavones of Decussocarpus rospigliosii as phosphodiesterases inhibitors. | 2007 Oct |
|
| Herpes virus inhibitory substances from Hypericum connatum Lam., a plant used in southern Brazil to treat oral lesions. | 2007 Sep 25 |
|
| Inhibition of prostaglandin E(2) production by anti-inflammatory hypericum perforatum extracts and constituents in RAW264.7 Mouse Macrophage Cells. | 2007 Sep 5 |
|
| Amentoflavone stimulates apoptosis in B16F-10 melanoma cells by regulating bcl-2, p53 as well as caspase-3 genes and regulates the nitric oxide as well as proinflammatory cytokine production in B16F-10 melanoma cells, tumor associated macrophages and peritoneal macrophages. | 2008 |
|
| Amentoflavone inhibits experimental tumor metastasis through a regulatory mechanism involving MMP-2, MMP-9, prolyl hydroxylase, lysyl oxidase, VEGF, ERK-1, ERK-2, STAT-1, NM23 and cytokines in lung tissues of C57BL/6 mice. | 2008 |
|
| Brain-to-plasma distribution ratio of the biflavone amentoflavone in the mouse. | 2008 Apr |
|
| Ethnopharmacological survey of six medicinal plants from Mali, West-Africa. | 2008 Dec 27 |
|
| Inhibition of tumor specific angiogenesis by amentoflavone. | 2008 Feb |
|
| Seco-terpenoids and other constituents from Elateriospermum tapos. | 2008 Feb |
|
| Flavones from Struthiola argentea with anthelmintic activity in vitro. | 2008 Jan |
|
| Biflavonoids isolated from Selaginella tamariscina regulate the expression of matrix metalloproteinase in human skin fibroblasts. | 2008 Jan 15 |
|
| Selaginellin A and B, two novel natural pigments isolated from Selaginella tamariscina. | 2008 Jul |
|
| Constituents of the Cuban endemic species Calophyllum pinetorum. | 2008 Jul |
|
| How to realize the linear scale-up process for rapid purification using high-performance counter-current chromatography. | 2008 Jun 20 |
|
| Modulatory effect of Byrsonima basiloba extracts on the mutagenicity of certain direct and indirect-acting mutagens in Salmonella typhimurium assays. | 2008 Mar |
|
| Antimicrobial activity of the crude extracts and five flavonoids from the twigs of Dorstenia barteri (Moraceae). | 2008 Mar 28 |
|
| Review on plants with CNS-effects used in traditional South African medicine against mental diseases. | 2008 Oct 28 |
|
| Chemical constituents of Hypericum adenotrichum Spach, an endemic Turkish species. | 2009 |
|
| Bioactive compounds of inhibiting xanthine oxidase from Selaginella labordei. | 2009 |
|
| Fatty acid synthase inhibition by amentoflavone induces apoptosis and antiproliferation in human breast cancer cells. | 2009 Aug |
|
| Free radical scavenging and antielastase activities of flavonoids from the fruits of Thuja orientalis. | 2009 Feb |
|
| Anti-Helicobacter pylori activity and immunostimulatory effect of extracts from Byrsonima crassa Nied. (Malpighiaceae). | 2009 Jan 16 |
|
| In vitro anti-neoplastic activity of the ethno-pharmaceutical plant Hypericum adenotrichum Spach endemic to Western Turkey. | 2009 Oct |
|
| Inhibitory effects of polyphenols on human cytochrome P450 3A4 and 2C9 activity. | 2010 Jan |
|
| Bioactive flavones and biflavones from Selaginella moellendorffii Hieron. | 2010 Jun |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Fri Dec 15 20:09:53 UTC 2023
by
admin
on
Fri Dec 15 20:09:53 UTC 2023
|
| Record UNII |
9I1VC79L77
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Official Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Systematic Name | English | ||
|
Code | English | ||
|
Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
|
DSLD |
3991 (Number of products:2)
Created by
admin on Fri Dec 15 20:09:53 UTC 2023 , Edited by admin on Fri Dec 15 20:09:53 UTC 2023
|
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
5281600
Created by
admin on Fri Dec 15 20:09:53 UTC 2023 , Edited by admin on Fri Dec 15 20:09:53 UTC 2023
|
PRIMARY | |||
|
DTXSID20167225
Created by
admin on Fri Dec 15 20:09:53 UTC 2023 , Edited by admin on Fri Dec 15 20:09:53 UTC 2023
|
PRIMARY | |||
|
AMENTOFLAVONE
Created by
admin on Fri Dec 15 20:09:53 UTC 2023 , Edited by admin on Fri Dec 15 20:09:53 UTC 2023
|
PRIMARY | |||
|
9I1VC79L77
Created by
admin on Fri Dec 15 20:09:53 UTC 2023 , Edited by admin on Fri Dec 15 20:09:53 UTC 2023
|
PRIMARY | |||
|
1617-53-4
Created by
admin on Fri Dec 15 20:09:53 UTC 2023 , Edited by admin on Fri Dec 15 20:09:53 UTC 2023
|
PRIMARY | |||
|
295677
Created by
admin on Fri Dec 15 20:09:53 UTC 2023 , Edited by admin on Fri Dec 15 20:09:53 UTC 2023
|
PRIMARY |