Callitris is a genus of coniferous trees in the Cupressaceae. There are 15 species in the genus, of which 13 are native to Australia and the other two (C. neocaledonica, C. sulcata) native to New Caledonia. The most widely used common name is cypress-pine. They are small to medium-sized trees or large shrubs. The wood of cypress-pines is light, soft and aromatic. It can be easily split and resists decay. It is used to make furniture, indoor and outdoor paneling, and fence posts. Cypress-pines are occasionally planted as ornamental trees, but their use is restricted by the high risks imposed by their very high flammability in bushfires. This study deals with Callitris wood oils from different species. A comparison between species from different collection areas was made. In the pharmacological part, assays were directed towards investigating the general anti-oxidant activity, cytotoxicity and the phagocytosis properties of the oils.